Senior Manager Clinical Operations - Early Development

About the Role

At [Employer hidden — sign up to reveal], we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions. As guided by Our Credo, [Employer hidden — sign up to reveal] is responsible to our employees who work with us throughout the world.

[Employer hidden — sign up to reveal] is an equal opportunity employer.

Job Description

The Senior Manager Clinical Operations for Early Development & Clinical Pharmacology (ED&CP) is accountable for strategic and operational management, and successful country execution of Early Development and/or Clinical Pharmacology (phase 0-IIa) trials across multiple therapeutic areas, including resource allocation, adherence to timelines and budget, compliance with relevant SOPs, policies, Health Care Compliance, and local regulatory requirements.

This is a Hybrid position (3 days per week onsite, 2 days WFH) located within commutable distance of High Wycombe, United Kingdom. (Note: [Employer hidden — sign up to reveal] office relocates to Maidenhead, UK in October 2026).

Responsibilities

• Providing line management to direct reports, including setting goals and objectives, conducting performance evaluations, and supporting talent development.
• Evaluating and forecasting resource needs for the assigned portfolio and coordinating plans with the Director, Early Development (EMEA/Americas).
• Supporting the flexible resourcing model by collaborating with Flex Resource managers to recruit, onboard, offboard, and assess flex staff performance.
• Interviewing, hiring, training, and developing team members.
• Ensuring understanding of relevant processes and procedural documents, and maintaining documented training compliance for direct reports.
• Supporting direct reports in issue resolution and stakeholder communications with Ethics Committees, Health Authorities, investigational sites, and study teams.
• Supporting local implementation of organizational changes and communicating priority shifts clearly.
• Reviewing and approving expenses in compliance with company policies.
• Demonstrating leadership behaviors aligned with [Employer hidden — sign up to reveal] Leadership Imperatives.
• Fostering an environment that encourages sharing of ideas, information, and best practices internally and externally.
• Providing coaching and mentorship, including conducting accompanied site visits as appropriate.
• Defining and delivering long-term strategy aligned with Global Development, ED&CP, and Innovative Medicine strategies.
• Attracting, planning, executing, and monitoring ED&CP clinical trials (feasibility to close-out) and maintaining inspection readiness for the portfolio.
• Ensuring operational objectives are met in conformance with ICH-GCP, relevant SOPs, and other procedural documents.
• Escalating and reporting suspected fraud, scientific or ethical misconduct, and healthcare compliance breaches.
• Shaping and maintaining strong relationships within ED&CP, the local GCO department, the Country Head/Local Operating Company, and other partners.
• Developing country ED&CP capabilities and collaborating with Project Delivery Leaders and Site Strategic Leaders.
• Leading a robust feasibility process and overseeing site selection.
• Leading regular metrics reviews and driving required follow-up actions.
• Ensuring adequate quality oversight and inspection readiness across therapeutic areas.
• Overseeing the local ED&CP budget and ensuring accurate financial reporting.
• Collaborating with the Country Head and Functional Managers to implement local processes and regulatory requirements.
• Leading development, evaluation, and implementation of new processes and systems.
• Fostering continuous improvement and innovation within the local ED&CP team.
• Modeling a Credo-based culture within the team.
• Mentoring / managing more junior Functional Managers.
• Assuming cross-border oversight as required.

Qualifications / Requirements

• Bachelor's degree or equivalent; life science (Biology, Chemistry, Biochemistry), Nursing, or Pharmacy preferred
• Minimum 10 years' clinical research experience in the pharmaceutical industry, a CRO, or an investigational site
• Early Development trial experience preferred
• At least 2 years' line management experience leading medium‑to‑large teams
• Strong communication and leadership skills with the ability to build team productivity and cohesion
• Experienced in recruiting, hiring, training, developing, and evaluating staff; solid decision‑making and financial management skills
• Skilled in issue resolution and in developing/implementing contingency plans
• Thorough knowledge of drug development, clinical research operations, and regulatory requirements, including ICH‑GCP and healthcare compliance
• Ability to synthesize and interpret data from multiple sources and communicate effectively with stakeholders
• Flexible and adaptable to fast‑paced, changing environments; able to operate with limited supervision
• Proficient in English with strong digital literacy, interpersonal, negotiation, organizational, and multitasking skills
• Able to work hybrid model: 3 days per week onsite and 2 days per week working from home

Benefits

We offer a competitive salary and extensive benefits package. The health and well-being of our employees is a priority, we have a flexible working environment as we value work-life balance. We offer career development opportunities.

Additional Information

[Employer hidden — sign up to reveal] Family of Companies are equal opportunity employers. We will ensure that individuals with disabilities are provided a reasonable accommodation.

#LI-Hybrid