Understanding inhibition of the gut microbiota metabolism of carnitine by pomegranate (KROON_Q22DTP)

🔒 Confidential Employer
Posted 3 May 2026
LOCATION
Norwich
TYPE
Full-time
LEVEL
Internship
SALARY
£15,609 / year
CATEGORY
Science & Research
This employer holds a UK Home Office sponsor license — sponsorship for this specific role is at the employer’s discretion

SKILLS

Gut microbiota research L-carnitine metabolism Polyphenol analysis In vitro colon models Shotgun metagenomics Bioinformatics LC-MS/MS qRT-PCR

FULL DESCRIPTION

Understanding inhibition of the gut microbiota metabolism of carnitine by pomegranate (KROON_Q22DTP)

[Employer hidden — view at passion-project.co.uk], Norwich, UK. PhD Studentship (4 years). Stipend: £15,609 per annum.

Project Summary

The human gut microbiota metabolises dietary L-carnitine to trimethylamine (TMA), which is converted to TMA-N-oxide (TMAO), a metabolite strongly associated with cardiovascular disease and other conditions. This studentship aims to understand how polyphenols from pomegranate inhibit this microbial metabolism using in vitro colon models, metagenomics, and analytical chemistry. The student will receive training in colon models, shotgun metagenomics, bioinformatics, PCR, qRT-PCR, and LC-MS/MS.

Requirements

  • First or Upper Second-class UK Honours degree (or equivalent) in a relevant field
  • English Language: IELTS 6.5 overall, 6 in each category (UEA Faculty of Science equivalent)
  • Interest in gut microbiota and health research

Funding

Norwich Research Park Biosciences Doctoral Training Partnership (NRPDTP) PhD studentship covering tuition fees, stipend (£15,609 for 2021/22), and £5,000 p.a. research training support grant. Open to UK and international candidates.

How to Apply

Visit https://biodtp.norwichresearchpark.ac.uk/ for eligibility and application details. Applications close 22 November 2021.

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