Senior Scientist II – LC-MS/MS

🔒 Confidential Employer
Posted 3 May 2026
LOCATION
Macclesfield
TYPE
Full-time
LEVEL
Mid-Senior level
CATEGORY
Science & Research
This employer holds a UK Home Office sponsor license — sponsorship for this specific role is at the employer’s discretion

SKILLS

LC-MS/MS Method Development Validation GLP GCP Sample Preparation Data Review Regulatory Compliance

FULL DESCRIPTION

Senior Scientist II – LC-MS/MS

Company: [Employer hidden — view at passion-project.co.uk]

Location: Macclesfield, Cheshire

Employment Type: Full-Time

Experience Level: Experienced

Role Overview

We are seeking a Senior Scientist II (Project Leader/Principal Investigator) – LC-MS/MS Bioanalysis (PK/PD)/Responsible Scientist to lead LC-MS/MS bioanalytical studies, ensuring scientific integrity, regulatory compliance, and successful study delivery.

Key Responsibilities

  • Act as scientific lead for LC-MS/MS bioanalytical studies conducted under GLP and GCP
  • Oversee method development, validation, and sample analysis
  • Review and interpret analytical data to ensure quality and compliance
  • Lead investigations into analytical issues and implement corrective actions
  • Ensure studies meet regulatory requirements and internal standards
  • Act as primary scientific contact for clients
  • Prepare, review, and approve study documentation and reports

Technical Expertise

  • Strong experience in LC-MS/MS method development and validation
  • Understanding of sample preparation techniques and analytical workflows
  • Ability to troubleshoot issues such as matrix effects, sensitivity, and assay variability

Qualifications and Experience

  • MSc or PhD in Analytical Chemistry or related field
  • 5 to 10 or more years of LC-MS/MS bioanalysis experience
  • Experience leading regulated studies in a GLP/GCP environment
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